Metastasis Zebrafish

Zebrafish Melanoma: From Initiation To Metastasis - YouTube
Physician-scientist Richard White says that animal models can help us understand how cancer spreads and how to treat it. ... View Video

PDF - Breast Cancer Research
RESEARCH ARTICLE Open Access Transforming growth factor-β signalling controls human breast cancer metastasis in a zebrafish xenograft model Yvette Drabsch1,2, Shuning He3, Long Zhang1,2,5, B Ewa Snaar-Jagalska3* and Peter ten Dijke1,2,4* ... Read More

Zebrafish Xenotransplant Model For Colorectal Cancer
Cell proliferation and metastasis. Immunodeficient mice have played an important role as host for cancer xenografts. However, variable survival, This SBIR aims to develop zebrafish (Danio rerio) as an alternate in vivo xenograft model for growing ... Fetch Content

Endothelial Cell-initiated Extravasation Of Cancer Cells ...
The extravasation of cancer cells, a key step for distant metastasis, is thought to be initiated by disruption of the endothelial barrier by malignant cancer cells. An The present study extended the zebrafish hematogenous metastasis model, and ... Doc Retrieval

Title
1 Title: A quantitative system for studying metastasis using transparent zebrafish Running title: Quantitation of metastasis in zebrafish Authors: ... View Full Source

Discriminating Different Cancer Cells Using A Zebrafish
Discriminating Different Cancer Cells Using a Zebrafish in Vivo Assay Karni S. Moshal, Karine F. Ferri-Lagneau, Jamil Haider, Pooja Pardhanani metastasis in a zebrafish tumor model. Proc. Natl. Acad. Sci. USA 2009, 106, 19485-19490. 9. ... Read Full Source

PROTOCOL Hypoxia-induced metastasis Model In Embryonic zebrafish
Hypoxia-induced metastasis model in embryonic zebrafish Pegah Rouhi 1,4, Lasse D Jensen , Ziquan Cao 2,4, developed a zebrafish metastasis model to dissect the detailed events of hypoxia-induced tumor cell invasion and metastasis ... Fetch Doc

RESEARCH Open Access ZebIAT, An Image Analysis Tool For ...
RESEARCH Open Access ZebIAT, an image analysis tool for registering zebrafish embryos and quantifying cancer metastasis Teppo Annila 1 , Eero Lihavainen 1 , Ines J Marques 2, Darren R Williams 3, Olli Yli-Harja 1, Andre Ribeiro 1* ... Access Doc

Evaluating Human Cancer Cell metastasis In zebrafish
RESEARCH ARTICLE Open Access Evaluating human cancer cell metastasis in zebrafish Yong Teng1*, Xiayang Xie2,3, Steven Walker2,3, David T White2,3, Jeff S Mumm2,3 and John K Cowell1 ... Fetch Full Source

High-Resolution Imaging Of The Dynamic Tumor Cell-Vascular ...
High-resolution imaging of the dynamic tumor cell-vascular interface in transparent zebrafish Konstantin Stoletov, Cell metastasis is a highly dynamic process that occurs in multiple High-Resolution Imaging of the Dynamic Tumor Cell-Vascular Interface in Transparent Zebrafish ... Read Full Source

A Zebrafish Model Of Uveal Melanoma The Harvard Community Has ...
A Zebrafish Model of Uveal Melanoma (Article begins on next page) The Harvard community has made this article openly available. Please share how this access benefits you. ... Document Retrieval

Zebrafish Swimming With Melanoma Growing On Their Bodies ...
Zebrafish at the Koch Center for Integrative Medicine at MIT used to study cancer and its mechanisms for metastasis. ... View Video

Invasiveness And metastasis Of Retinoblastoma In An ...
Www.nature.comscientificreports SCINTIIC REPORTS 5:10351 DOI: 10.1038srep10351 3 zebrafish body, retinoblastoma metastasis in the contralateral eye and in remote organs could be detected ... Read Here

Kinase Insert Domain Receptor - Wikipedia, The Free Encyclopedia
Kinase insert domain receptor (KDR, a type III receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF receptor. ... Read Article

A Fresh Look At zebrafish From The Perspective Of Cancer Research
REVIEW Open Access A fresh look at zebrafish from the perspective of cancer research Shuai Zhao1, Jian Huang1* and Jun Ye2* Abstract Zebrafish represent a vertebrate model organism that has been widely, and increasingly, employed over the last ... Access Full Source

Hypoxia-induced Pathological Angiogenesis Mediates Tumor Cell ...
Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model Samantha Lin Chiou Leea,b,1, Pegah Rouhia,1, Lasse Dahl Jensena, Danfang Zhanga, Hong Jia, Giselbert Hauptmannc,d, ... Content Retrieval

Modeling Tumor Angiogenesis In Zebrafish - InTech
Tumor Angiogenesis 168 organs and tissues in vivo (Thisse and Zon, 2002). These attributes have led to the emergence of the zebrafish as a preeminent embryological model. ... Get Content Here

NCI Zebrafish Studies Zebrafish Models Of Cancer: Harnessing ...
Zebrafish Models of Cancer: Harnessing Genetics to Dissect Oncogenic Pathways and Identify Therapeutic Vulnerabilities Tom Look Zebrafish Shed Light on Metastasis: Metastasis is responsible for the vast majority of cancer deaths, yet the ... Read More

Hypoxia-induced metastasis Model In Embryonic zebrafish
Additionally, hypoxia-induced metastasis in zebrafish embryos provides an outstanding opportunity to define signal-ing components in the host, which facilitates tumor invasion, dis-semination and metastasis using specific morpholino intervention ... View Doc

Genetic Depletion And Pharmacological Targeting Of Av ...
RESEARCH ARTICLE Open Access Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse ... Fetch Document

Pathological Angiogenesis Facilitates Tumor Cell ...
Zebrafish Metastasis Model At the early stage of development, zebrafish embryos lack pigmentation and remain immune privileged.31 The Tg(fli1:EGFP) zebrafish strain allows direct visualiza-tion of vascular development without any ... Document Retrieval

Neutrophil-Mediated Experimental Metastasis Is Enhanced By ...
Neutrophil-Mediated Experimental Metastasis Is Enhanced by VEGFR Inhibition in a Zebrafish Xenograft Model (Article begins on next page) The Harvard community has made this article openly available. ... Content Retrieval